Convenient linkages to major transportation routes through the Lancaster metropolitan area are available to Township residents and businesses. Two Federal (US Route 222 and 30), and seven State roads (PA Routes 283, 4011, 72, 501, 272, 23 and 230) connect the Township to the region. The proximity of the City of Lancaster to many larger eastern cities, provides Manheim Township residents with convenient access to Philadelphia, Baltimore, and Wilmington, and reasonable access to New York, Pittsburgh and Washington, D.C.
Airline and commuter rail service is also available to residents of Manheim Township. The Township hosts the Lancaster Airport, with daily commuter air service. The Lancaster Amtrak Station provides daily east and west rail service on the Keystone Corridor.